The key difference between epimysium and fascia is that epimysium is the connective tissue that surrounds a single muscle while fascia is the connective tissue that attaches, stabilizes, encloses, and separates muscles and other internal organs.
Connective tissue is one of the four types of tissues we have in our body. It is located between all the other tissues. Therefore, it is the most abundant and widely distributed tissue. Fascia and epimysium are two types of connective tissues. Epimysium is the connective tissue that surrounds an entire muscle. Fascia is the connective tissue that is on the epimysium surrounding and separating muscles. Epimysium is continuous with the fascia.
