The key difference between feedback inhibition and feedback repression is that in feedback inhibition, the product inhibits the enzyme by binding with the active site of the enzyme and prevents the formation of the substrate-enzyme complex. Meanwhile, in feedback repression, end product inhibits the enzyme by inhibiting the production of the enzyme at the gene level.
Enzymes participate in biochemical reactions. They act as biocatalysts and speed up the reactions. Also, they can be inhibited in different ways. Feedback inhibition and feedback repression are two ways of enzyme inhibition. In feedback inhibition, the product itself inhibits the enzyme in order to control the amount of product. The product binds with the active site of the enzyme and prevents the binding of the substrate with the enzyme. In feedback repression, the end product inhibits the production of the enzyme at the gene level.